Synthesis and biological evaluation of 5-substituted derivatives of benzimidazole
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چکیده
منابع مشابه
Synthesis and biological evaluation of benzimidazole-5-carbohydrazide derivatives as antimalarial, cytotoxic and antitubercular agents.
A series of N'-substituted-2-(5-nitrofuran or 5-nitrothiophen-2-yl)-3H-benzo[d]imidazole-5-carbohydrazide derivatives were synthesized and investigated for their abilities to inhibit β-hematin formation, hemoglobin hydrolysis and in vivo for their antimalarial efficacy in rodent Plasmodium berghei. Selected analogues were screened for their antitubercular activity against sensitive MTB H(37)Rv ...
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ژورنال
عنوان ژورنال: Journal of the Serbian Chemical Society
سال: 2014
ISSN: 0352-5139,1820-7421
DOI: 10.2298/jsc130418058v